About me
I am a postdoctoral scholar in the lab of Jay Debnath, MD in the Department of Pathology at the University of California, San Francisco. I am studying the roles of autophagy in angiogenesis and vascular development using in vivo and in vitro methods.
I obtained my PhD in April 2016 in the lab of Michael T. Lewis, PhD in the Department of Molecular and Cellular Biology at Baylor College of Medicine (Houston TX). My thesis project focused on the epithelial and stromal functions of hedgehog network genes in mammary gland development. I also have an ongoing collaboration elucidating functions of hedgehog network genes in fertility with Yi Athena Ren, PhD and JoAnne Richards, PhD at BCM.
My primary research interests are understanding mechanisms and genetics of cell-cell and tissue-tissue crosstalk in development and disease. In addition to research, I am passionate about teaching and mentoring students.
Contact Info
teresa.monkkonen@ucsf.edu
teresa.monkkonen@gmail.com
LinkedIn
I obtained my PhD in April 2016 in the lab of Michael T. Lewis, PhD in the Department of Molecular and Cellular Biology at Baylor College of Medicine (Houston TX). My thesis project focused on the epithelial and stromal functions of hedgehog network genes in mammary gland development. I also have an ongoing collaboration elucidating functions of hedgehog network genes in fertility with Yi Athena Ren, PhD and JoAnne Richards, PhD at BCM.
My primary research interests are understanding mechanisms and genetics of cell-cell and tissue-tissue crosstalk in development and disease. In addition to research, I am passionate about teaching and mentoring students.
Contact Info
teresa.monkkonen@ucsf.edu
teresa.monkkonen@gmail.com
Publications
1. Monkkonen, T; Landua, JD; Visbal, AP; and Lewis, MT. Epithelial and Non-Epithelial Patched-1 (Ptch1) Play Opposing Roles to Regulate Proliferation and Morphogenesis of the Mouse Mammary Gland. In revision, Development.
2. Monkkonen, T; Lewis, MT. New Paradigms for the Hedgehog Signaling Network in Mammary Gland Development and Breast Cancer. In revision, BBA Reviews on Cancer.
3. Harvey SB, Zhang Y, Wilson-Grady J, Monkkonen T, Nelsestuen GL, Kasthuri RS, Verneris MR, Lund TC, Ely EW, Bernard GR, Zeisler H, Homoncik M, Jilma B, Swan T, Kellogg TA (2008) O-Glycoside Biomarker of Apolipoprotein C3: Responsiveness to Obesity, Bariatric Surgery, and Therapy with Metformin, to Chronic or Severe Liver Disease and to Mortality in Severe Sepsis and Graft vs Host Disease. J Proteome Res 8 (2):603–612.
4. Zhang, Y, Oetting WS, Harvey SB, Stone MD, Monkkonen T, Matas AJ, Cosio FG, Nelsestuen GL. Urinary Peptide Patterns in Native Kidneys and Kidney Allografts. Transplantation 87 (12): 1807-183.
2. Monkkonen, T; Lewis, MT. New Paradigms for the Hedgehog Signaling Network in Mammary Gland Development and Breast Cancer. In revision, BBA Reviews on Cancer.
3. Harvey SB, Zhang Y, Wilson-Grady J, Monkkonen T, Nelsestuen GL, Kasthuri RS, Verneris MR, Lund TC, Ely EW, Bernard GR, Zeisler H, Homoncik M, Jilma B, Swan T, Kellogg TA (2008) O-Glycoside Biomarker of Apolipoprotein C3: Responsiveness to Obesity, Bariatric Surgery, and Therapy with Metformin, to Chronic or Severe Liver Disease and to Mortality in Severe Sepsis and Graft vs Host Disease. J Proteome Res 8 (2):603–612.
4. Zhang, Y, Oetting WS, Harvey SB, Stone MD, Monkkonen T, Matas AJ, Cosio FG, Nelsestuen GL. Urinary Peptide Patterns in Native Kidneys and Kidney Allografts. Transplantation 87 (12): 1807-183.
Previous Research Projects and Mentors
2010-2016: Dr. Michael T. Lewis
Dept. of Molecular and Cellular Biology & Lester and Sue Smith Breast Center
Baylor College of Medicine, Houston, TX
I studied the effects of conditional ablation of Patched-1 in the mammary epithelium, and in stromal cell types with respect to virgin mammary gland development. I also collaborated with JoAnne RIchards and Yi Athena Ren at BCM to define stromal functions of Patched-1 in ovarian development and ovulation.
Dissertation title: Epithelial, Stromal, and Systemic Functions of Patched 1 in Mammary Gland Development.
2007-2008: Dr. Gary L. Nelsestuen
Dept. of Biochemistry, University of Minnesota, St. Paul, MN
I applied proteomics techniques (MALDI-TOF) to assay plasma and urine proteomes of patients with different metabolic diseases.
2006-2007: Dr. James A. McNew
Dept. of Biochemistry and Cell Biology, Rice University, Houston TX
I did a senior honors thesis studying C. elegans SNARE proteins and vesicle fusion using reconstituted liposomes.
Dept. of Molecular and Cellular Biology & Lester and Sue Smith Breast Center
Baylor College of Medicine, Houston, TX
I studied the effects of conditional ablation of Patched-1 in the mammary epithelium, and in stromal cell types with respect to virgin mammary gland development. I also collaborated with JoAnne RIchards and Yi Athena Ren at BCM to define stromal functions of Patched-1 in ovarian development and ovulation.
Dissertation title: Epithelial, Stromal, and Systemic Functions of Patched 1 in Mammary Gland Development.
2007-2008: Dr. Gary L. Nelsestuen
Dept. of Biochemistry, University of Minnesota, St. Paul, MN
I applied proteomics techniques (MALDI-TOF) to assay plasma and urine proteomes of patients with different metabolic diseases.
2006-2007: Dr. James A. McNew
Dept. of Biochemistry and Cell Biology, Rice University, Houston TX
I did a senior honors thesis studying C. elegans SNARE proteins and vesicle fusion using reconstituted liposomes.
